Abstract

Hemorrhoids, a prevalent medical condition impacting millions globally, fre quently necessitate effective yet minimally invasive treatment methods. This review delves into the prospects of utilizing oral catechins and epicatechins, naturally occurring polyphenolic compounds present in diverse dietary sources, as an innova tive avenue for addressing hemorrhoids. These compounds have antioxidant and anti-inflammatory attributes, which may help alleviate hemorrhoid symptoms. An understanding of the anatomy and pathophysiology of hemorrhoids, emphasizing the need for accessible and versatile treatment options. Subsequently, the focus turns to a detailed exploration of catechin and epicatechin, encompassing their chemical com position, natural origins, and mechanism of action. The core of this review presents a comprehensive analysis of the existing literature, including randomized controlled trials that examine the efficacy of oral catechin and epicatechin supplementation in alleviating hemorrhoidal symptoms. To conclude, this article highlights the potential of oral catechin and epicatechin supplementation as a non-invasive and natural approach to managing hemorrhoids. While promising findings have emerged, further research is essential to solidify their role in hemorrhoid treatment. The comprehen sive assessment of existing literature and critical evaluation of these compounds’ mechanism of action provides valuable insights into their viability as a treatment modality for this common and often distressing medical concern.