Abstract

Aim: This is a post marketing surveillance carried out to assess the clinical safety and efficacy of S(-) Amlodipine in patients with hypertension.

Materials & Methods: 81 practicing physicians throughout India collaborated in the recruitment of 235 hypertensive patients over a period of 6 months. Hypertensive patients were administered S(-) Amlodipine (2.5 or 5 mg). The fall in Blood pressure was observed at the end of 30 days. Serious adverse events were also reviewed.

Results: Significant reduction was observed in the systolic and diastolic blood pressure after treatment with S(-) Amlodipine for a period of 30 days. More than 80% of the patients on S(-) Amlodipine monotherapy achieved the JNC 7 goal in standing, sitting and supine positions.

Conclusion: These results are reassuring and provide further evidence of the safety and efficacy of S(-) Amlodipine in the management of hypertension.